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NDUFS8

Official Full Name
NADH:ubiquinone oxidoreductase core subunit S8
Organism
Homo sapiens
GeneID
4728
Background
This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010]
Synonyms
TYKY; CI-23k; CI23KD; MC1DN2;

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