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NACA


Official Full Name
nascent polypeptide associated complex subunit alpha
Organism
Homo sapiens
Gene ID
4666
Background
This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016]
Synonyms
HSD48; NACA1; skNAC; NAC-alpha

Cat.No. Product Name Price
SHW015422 shRNA set against Danio rerio NACA (NM_173264) Inquiry
SHH214769 shRNA set against Mouse Naca(NM_013608.3) Inquiry
SHH348916 shRNA set against Mouse NACA (NM_013608.3) Inquiry
SHH348920 shRNA set against Rat NACA (NM_001105939.2) Inquiry
SHW003646 shRNA set against Chicken NACA (NM_001276303) Inquiry
SHW013669 shRNA set against Danio rerio NACA (NM_001193352) Inquiry
Cat.No. Product Name Price
CDCB176897 Danio rerio NACA ORF Clone (NM_173264) Inquiry
CDCR251974 Mouse Naca ORF Clone(NM_013608.3) Inquiry
CDFG019165 Mouse Naca cDNA Clone(NM_001113199.1) Inquiry
CDFH012130 Human NACA cDNA Clone(NM_001113202.1) Inquiry
CDFR005714 Rat Naca cDNA Clone(NM_001105939.2) Inquiry
MiUTR1M-07482 NACA miRNA 3'UTR clone Inquiry
MiUTR3H-03967 NACA miRNA 3'UTR clone Inquiry
MiUTR3H-03968 NACA miRNA 3'UTR clone Inquiry
SKO0616 NACA Validated sgRNA vector Inquiry
CDCB165121 Chicken NACA ORF Clone (NM_001276303) Inquiry
CDCB175144 Danio rerio NACA ORF Clone (NM_001193352) Inquiry
CDCB181740 Rabbit NACA ORF clone (XM_008256683.1) Inquiry
CDCR347907 Human NACA ORF Clone(NM_001113202.1) Inquiry
CDCR347909 Human NACA ORF Clone(NM_001113203.2) Inquiry
CDCR372743 Rat Naca ORF Clone(NM_001105939.2) Inquiry
CDCR382739 Mouse Naca ORF Clone(NM_001113199.1) Inquiry
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