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NUS1


Official Full Name
NUS1 dehydrodolichyl diphosphate synthase subunit
Organism
Homo sapiens
Gene ID
116150
Background
This gene encodes a type I single transmembrane domain receptor, which is a subunit of cis-prenyltransferase, and serves as a specific receptor for the neural and cardiovascular regulator Nogo-B. The encoded protein is essential for dolichol synthesis and protein glycosylation. This gene is highly expressed in non-small cell lung carcinomas as well as estrogen receptor-alpha positive breast cancer cells where it promotes epithelial mesenchymal transition. This gene is associated with the poor prognosis of human hepatocellular carcinoma patients. Naturally occurring mutations in this gene cause a congenital disorder of glycosylation and are associated with epilepsy. A knockout of the orthologous gene in mice causes embryonic lethality before day 6.5. Pseudogenes of this gene have been defined on chromosomes 13 and X. [provided by RefSeq, May 2017]
Synonyms
NgBR; MRD55; CDG1AA; C6orf68; TANGO14; MGC:7199

Cat.No. Product Name Price
SHH356624 shRNA set against Human NUS1 (NM_138459.3) Inquiry
SHH356628 shRNA set against Mouse NUS1 (NM_030250.2) Inquiry
SHH356632 shRNA set against Rat NUS1 (NM_001164157.1) Inquiry
SHW006388 shRNA set against Danio rerio NUS1 (NM_001002356) Inquiry
Cat.No. Product Name Price
MiUTR1H-07002 NUS1 miRNA 3'UTR clone Inquiry
CDCB159928 Human NUS1 ORF clone (BC013026) Inquiry
CDCB167863 Danio rerio NUS1 ORF Clone (NM_001002356) Inquiry
CDCB194087 Rabbit NUS1 ORF clone (XM_008263427.1) Inquiry
CDCR263541 Mouse Nus1 ORF Clone(NM_030250.2) Inquiry
CDCS416791 Human NUS1 ORF Clone (BC013026) Inquiry
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