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Ntan1


Official Full Name
N-terminal Asn amidase
Organism
Mus musculus
Gene ID
18203
Background
The protein encoded by this gene functions in a step-wise protein degradation process through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asparagine residues on proteins to produce N-terminal L-Aspartate. L-Aspartate substrates are subsequently conjugated to L-Arginine, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Mice with a knock-out of this gene are viable, fertile, and outwardly normal, but show impairments in spontaneous activity and spatial memory, relative to their wild-type counterparts. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Synonyms
Ntan1; PNAA; PNAD

Cat.No. Product Name Price
SHH355640 shRNA set against Human NTAN1 (NM_173474.3) Inquiry
SHH355644 shRNA set against Mouse NTAN1 (NM_010946.3) Inquiry
SHH355648 shRNA set against Rat NTAN1 (NM_001025124.1) Inquiry
SHR024618 shRNA set against Mouse Ntan1(NM_010946.3) Inquiry
SHW016989 shRNA set against Danio rerio NTAN1 (NM_200851) Inquiry
Cat.No. Product Name Price
CDFR003852 Rat Ntan1 cDNA Clone(NM_001025124.1) Inquiry
MiUTR1M-07854 NTAN1 miRNA 3'UTR clone Inquiry
MiUTR1R-06442 NTAN1 miRNA 3'UTR clone Inquiry
MiUTR3H-15617 NTAN1 miRNA 3'UTR clone Inquiry
CDCB158936 Human NTAN1 ORF clone (BC017336) Inquiry
CDCB178464 Danio rerio NTAN1 ORF Clone (NM_200851) Inquiry
CDCB183750 Rabbit NTAN1 ORF clone (XM_002711780.2) Inquiry
CDCL140281 Mouse Ntan1 ORF clone (NM_010946.3) Inquiry
CDCR370876 Rat Ntan1 ORF Clone(NM_001025124.1) Inquiry
CDCS417386 Human NTAN1 ORF Clone (BC017336) Inquiry
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