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NSUN2

Official Full Name
NOP2/Sun RNA methyltransferase 2
Organism
Homo sapiens
GeneID
54888
Background
This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]
Synonyms
MISU; MRT5; SAKI; TRM4;

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