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NPHP1


Official Full Name
nephrocystin 1
Organism
Homo sapiens
Gene ID
4867
Background
This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
NPH1; JBTS4; SLSN1

Cat.No. Product Name Price
SHH354212 shRNA set against Human NPHP1 (NM_000272.3) Inquiry
SHH354219 shRNA set against Mouse NPHP1 (NM_016902.3) Inquiry
SHH354220 shRNA set against Rat NPHP1 (NM_001106506.1) Inquiry
SHR018084 shRNA set against Mouse Nphp1(NM_016902.3) Inquiry
SHW003244 shRNA set against Chicken NPHP1 (NM_001199429) Inquiry
SHW010512 shRNA set against Danio rerio NPHP1 (NM_001077170) Inquiry
Cat.No. Product Name Price
MiUTR3H-08967 NPHP1 miRNA 3'UTR clone Inquiry
MiUTR3H-08965 NPHP1 miRNA 3'UTR clone Inquiry
MiUTR3H-08964 NPHP1 miRNA 3'UTR clone Inquiry
MiUTR1M-07771 NPHP1 miRNA 3'UTR clone Inquiry
CDFR006238 Rat Nphp1 cDNA Clone(NM_001106506.1) Inquiry
CDFL008497 Mouse Nphp1 cDNA Clone(NM_016902.3) Inquiry
CDFH012716 Human NPHP1 cDNA Clone(NM_001128179.1) Inquiry
CDFH012715 Human NPHP1 cDNA Clone(NM_001128178.1) Inquiry
CDFG013764 Human NPHP1 cDNA Clone(NM_207181.2) Inquiry
MiUTR3H-08966 NPHP1 miRNA 3'UTR clone Inquiry
CDCS405539 Human NPHP1 ORF Clone (BC062574) Inquiry
CDCR373291 Rat Nphp1 ORF Clone(NM_001106506.1) Inquiry
CDCR348974 Human NPHP1 ORF Clone(NM_001128179.1) Inquiry
CDCR253258 Mouse Nphp1 ORF Clone(NM_016902.3) Inquiry
CDCL139413 Human NPHP1 ORF clone (NM_207181.2) Inquiry
CDCL139411 Mouse NPHP1 ORF clone (NM_001128178.1) Inquiry
CDCB186683 Rabbit NPHP1 ORF clone (XM_008253984.1) Inquiry
CDCB171987 Danio rerio NPHP1 ORF Clone (NM_001077170) Inquiry
CDCB164719 Chicken NPHP1 ORF Clone (NM_001199429) Inquiry
CDCS405538 Human NPHP1 ORF Clone (BC009789) Inquiry
CDCB158093 Human NPHP1 ORF clone (BC062574) Inquiry
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