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NODAL


Official Full Name
nodal growth differentiation factor
Organism
Homo sapiens
Gene ID
4838
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016]
Synonyms
HTX5

Cat.No. Product Name Price
SHH353464 shRNA set against Human NODAL (NM_018055.4) Inquiry
SHH353468 shRNA set against Mouse NODAL (NM_013611.4) Inquiry
SHH353472 shRNA set against Rat NODAL (NM_001106394.1) Inquiry
Cat.No. Product Name Price
CDCL185498 Human NODAL ORF clone(NM_018055.4) Inquiry
CDFL008449 Mouse Nodal cDNA Clone(NM_013611.4) Inquiry
CDFR006130 Rat Nodal cDNA Clone(NM_001106394.1) Inquiry
MiUTR3H-04006 NODAL miRNA 3'UTR clone Inquiry
CDCB192105 Rabbit NODAL ORF clone (XM_002718435.1) Inquiry
CDCR251979 Mouse Nodal ORF Clone(NM_013611.4) Inquiry
CDCR373195 Rat Nodal ORF Clone(NM_001106394.1) Inquiry
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