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NLRP14


Official Full Name
NLR family pyrin domain containing 14
Organism
Homo sapiens
Gene ID
338323
Background
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]
Synonyms
NOD5; PAN8; GC-LRR; NALP14; CLR11.2

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