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nipblb


Official Full Name
NIPBL cohesin loading factor b
Organism
Danio rerio
Gene ID
794108
Background
Enables chromatin loop anchoring activity. Acts upstream of or within several processes, including embryonic morphogenesis; neuron cellular homeostasis; and regulation of canonical Wnt signaling pathway. Predicted to be located in nucleus. Predicted to be part of Scc2-Scc4 cohesin loading complex. Is expressed in several structures, including Kupffer's vesicle; blastoderm; blastodisc; central nervous system; and lateral plate mesoderm. Used to study Cornelia de Lange syndrome. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome and Cornelia de Lange syndrome 1. Orthologous to human NIPBL (NIPBL cohesin loading factor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
nipbl; nipbla; fc12g03; wu:fc12g03; wu:fi33d08

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