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NDUFA1


Official Full Name
NADH:ubiquinone oxidoreductase subunit A1
Organism
Homo sapiens
Gene ID
4694
Background
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008]
Synonyms
MWFE; ZNF183; CI-MWFE; MC1DN12

Cat.No. Product Name Price
SHH350468 shRNA set against Rat NDUFA1 (NM_001108813.2) Inquiry
SHH350460 shRNA set against Human NDUFA1 (NM_004541.3) Inquiry
SHH350464 shRNA set against Mouse NDUFA1 (NM_019443.2) Inquiry
SHR004320 shRNA set against Mouse Ndufa1(NM_019443.2) Inquiry
SHR004576 shRNA set against Human NDUFA1(NM_004541.3) Inquiry
SHW004551 shRNA set against Chicken NDUFA1 (NM_001302115) Inquiry
SHW006263 shRNA set against Danio rerio NDUFA1 (NM_001002153) Inquiry
SHW013515 shRNA set against Danio rerio NDUFA1 (NM_001167855) Inquiry
Cat.No. Product Name Price
MiUTR1H-06695 NDUFA1 miRNA 3'UTR clone Inquiry
MiUTR1M-07550 NDUFA1 miRNA 3'UTR clone Inquiry
SKO0620 NDUFA1 Validated sgRNA vector Inquiry
CDCB166026 Chicken NDUFA1 ORF Clone (NM_001302115) Inquiry
CDCB167738 Danio rerio NDUFA1 ORF Clone (NM_001002153) Inquiry
CDCB174990 Danio rerio NDUFA1 ORF Clone (NM_001167855) Inquiry
CDCL137135 Mouse Ndufa1 ORF clone (NM_019443.2) Inquiry
CDCR375436 Rat Ndufa1 ORF Clone(NM_001108813.2) Inquiry
CDCS411839 Human NDUFA1 ORF Clone (BC000266) Inquiry
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