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NAIP


Official Full Name
NLR family apoptosis inhibitory protein
Organism
Homo sapiens
Gene ID
4671
Background
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Synonyms
BIRC1; NLRB1; psiNAIP

Cat.No. Product Name Price
SHH215183 shRNA set against Human NAIP(NM_022892.1) Inquiry
SHH215201 shRNA set against Human NAIP(NM_004536.2) Inquiry
SHH349092 shRNA set against Mouse NAIP (NM_021545.1) Inquiry
SHH349100 shRNA set against Mouse Naip1 (NM_008670.2) Inquiry
Cat.No. Product Name Price
CDFG004012 Human NAIP cDNA Clone(NM_022892.1) Inquiry
MiUTR1H-06626 NAIP miRNA 3'UTR clone Inquiry
MiUTR1H-06627 NAIP miRNA 3'UTR clone Inquiry
MiUTR1M-07485 NAIP1 miRNA 3'UTR clone Inquiry
CDCB194232 Rabbit NAIP ORF clone (XM_008262325.1) Inquiry
CDCH391311 Human NAIP ORF clone(NM_004536.2) Inquiry
CDCL136407 Mouse NAIP ORF clone (NM_022892.1) Inquiry
CDCL136409 Mouse Naip1 ORF clone (NM_008670.2) Inquiry
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