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MTA1


Official Full Name
metastasis associated 1
Organism
Homo sapiens
Gene ID
9112
Background
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Synonyms
MOR173-1

Cat.No. Product Name Price
SHH204923 shRNA set against Mouse Mta1(NM_054081.2) Inquiry
SHH204931 shRNA set against Rat Mta1(NM_022588.1) Inquiry
SHH204959 shRNA set against Human MTA1(NM_004689.3) Inquiry
SHH346052 shRNA set against Human MTA1 (NM_004689.3) Inquiry
SHH346056 shRNA set against Mouse MTA1 (NM_054081.2) Inquiry
SHH346060 shRNA set against Rat MTA1 (NM_022588.1) Inquiry
SHW001106 shRNA set against Chicken MTA1 (NM_001012953) Inquiry
Cat.No. Product Name Price
CDFL007933 Mouse Mta1 cDNA Clone(NM_054081.2) Inquiry
CDFR012021 Rat Mta1 cDNA Clone(NM_022588.1) Inquiry
MiUTR1H-06496 MTA1 miRNA 3'UTR clone Inquiry
MiUTR1M-07347 MTA1 miRNA 3'UTR clone Inquiry
MiUTR1R-04029 MTA1 miRNA 3'UTR clone Inquiry
CDCB162581 Chicken MTA1 ORF Clone (NM_001012953) Inquiry
CDCB186737 Rabbit MTA1 ORF clone (XM_008253662.1) Inquiry
CDCL134791 Human MTA1 ORF clone (NM_001203258.1) Inquiry
CDCL134797 Human Mta1 ORF clone (NM_054081.2) Inquiry
CDCR379068 Rat Mta1 ORF Clone(NM_022588.1) Inquiry
CDCS409590 Human MTA1 ORF Clone (BC006177) Inquiry
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