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MS4A2


Official Full Name
membrane spanning 4-domains A2
Organism
Homo sapiens
Gene ID
2206
Background
The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. [provided by RefSeq, Mar 2012]
Synonyms
APY; IGEL; IGER; ATOPY; FCERI; IGHER; FCER1B

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SHH202943 shRNA set against Rat Ms4a2(NM_012845.1) Inquiry
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SHH345480 shRNA set against Human MS4A2 (NM_000139.4) Inquiry
SHH345484 shRNA set against Mouse MS4A2 (NM_013516.1) Inquiry
SHH345488 shRNA set against Rat MS4A2 (NM_012845.1) Inquiry
Cat.No. Product Name Price
CDFR010701 Rat Ms4a2 cDNA Clone(NM_012845.1) Inquiry
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MiUTR1R-04015 MS4A2 miRNA 3'UTR clone Inquiry
CDCB187042 Rabbit MS4A2 ORF clone (XM_008271826.1) Inquiry
CDCL134475 Human MS4A2 ORF clone (NM_001256916.1) Inquiry
CDCL134479 Human Ms4a2 ORF clone (NM_013516.1) Inquiry
CDCL185396 Mouse MS4A2 ORF clone(NM_012845.1) Inquiry
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