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MRPS12


Official Full Name
mitochondrial ribosomal protein S12
Organism
Homo sapiens
Gene ID
6183
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene; all three variants encode the same protein. [provided by RefSeq, Jul 2008]
Synonyms
RPS12; uS12m; RPMS12; RPSM12; MPR-S12; MT-RPS12

Cat.No. Product Name Price
SHH201521 shRNA set against Mouse Mrps12(NM_011885.4) Inquiry
SHH201539 shRNA set against Human MRPS12(NM_021107.1) Inquiry
SHH202349 shRNA set against Human MRPS34(NM_023936.1) Inquiry
SHH202367 shRNA set against Mouse Mrps34(NM_023260.1) Inquiry
SHH345072 shRNA set against Human MRPS12 (NM_021107.1) Inquiry
SHH345076 shRNA set against Mouse MRPS12 (NM_011885.4) Inquiry
SHH345080 shRNA set against Rat MRPS12 (NM_001106239.1) Inquiry
SHH345308 shRNA set against Human MRPS34 (NM_023936.1) Inquiry
SHH345312 shRNA set against Mouse MRPS34 (NM_023260.1) Inquiry
SHH345316 shRNA set against Rat MRPS34 (NM_001105771.1) Inquiry
SHW003923 shRNA set against Chicken MRPS34 (NM_001277597) Inquiry
SHW007648 shRNA set against Danio rerio MRPS34 (NM_001007376) Inquiry
Cat.No. Product Name Price
CDFG004141 Human MRPS34 cDNA Clone(NM_023936.1) Inquiry
MiUTR3H-05562 MRPS12 miRNA 3'UTR clone Inquiry
MiUTR1M-07309 MRPS34 miRNA 3'UTR clone Inquiry
MiUTR1M-07294 MRPS12 miRNA 3'UTR clone Inquiry
MiUTR1H-06457 MRPS34 miRNA 3'UTR clone Inquiry
CDFR005997 Rat Mrps12 cDNA Clone(NM_001106239.1) Inquiry
CDFR005502 Rat Mrps34 cDNA Clone(NM_001105771.1) Inquiry
CDFG006810 Human MRPS12 cDNA Clone(NM_033363.1) Inquiry
CDFG006808 Human MRPS12 cDNA Clone(NM_033363.1) Inquiry
MiUTR3H-05563 MRPS12 miRNA 3'UTR clone Inquiry
MiUTR3H-05564 MRPS12 miRNA 3'UTR clone Inquiry
CDCS415622 Human MRPS34 ORF Clone (BC001182) Inquiry
CDCL134365 Human MRPS34 ORF clone (NM_023936.1) Inquiry
CDFG003210 Human MRPS12 cDNA Clone(NM_021107.1) Inquiry
CDCR373007 Rat Mrps12 ORF Clone(NM_001106239.1) Inquiry
CDCR372591 Rat Mrps34 ORF Clone(NM_001105771.1) Inquiry
CDCL134367 Human Mrps34 ORF clone (NM_023260.1) Inquiry
CDCH390497 Mouse MRPS12 ORF clone(NM_011885.4) Inquiry
CDCB182625 Rabbit MRPS12 ORF clone (XM_002711456.2) Inquiry
CDCB169123 Danio rerio MRPS34 ORF Clone (NM_001007376) Inquiry
CDCB165398 Chicken MRPS34 ORF Clone (NM_001277597) Inquiry
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