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MID1


Official Full Name
midline 1
Organism
Homo sapiens
Gene ID
4281
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
Synonyms
OS; FXY; OSX; GBBB; OGS1; XPRF; BBBG1; GBBB1; MIDIN; RNF59; ZNFXY; TRIM18

Cat.No. Product Name Price
SHH189587 shRNA set against Rat Mid1(NM_022927.1) Inquiry
SHH189515 shRNA set against Mouse Mid1(NM_010797.2) Inquiry
SHH189569 shRNA set against Mouse Mid1(NM_183151.1) Inquiry
SHH341907 shRNA set against Human MID1 (NM_000381.3) Inquiry
SHH341911 shRNA set against Mouse MID1 (NM_010797.2) Inquiry
SHH341915 shRNA set against Rat MID1 (NM_022927.1) Inquiry
SHW004648 shRNA set against Chicken MID1 (NM_204129) Inquiry
Cat.No. Product Name Price
CDFL007626 Mouse Mid1 cDNA Clone(NM_183151.1) Inquiry
CDFR012151 Rat Mid1 cDNA Clone(NM_022927.1) Inquiry
MiUTR1M-07111 MID1 miRNA 3'UTR clone Inquiry
MiUTR1M-07112 MID1 miRNA 3'UTR clone Inquiry
MiUTR1R-03915 MID1 miRNA 3'UTR clone Inquiry
CDCB157803 Human MID1 ORF clone (BC053626) Inquiry
CDCB166123 Chicken MID1 ORF Clone (NM_204129) Inquiry
CDCL132639 Human Mid1 ORF clone (NM_183151.1) Inquiry
CDCL132645 Human MID1 ORF clone (NM_001193279.1) Inquiry
CDCL132647 Mouse MID1 ORF clone (NM_001193281.1) Inquiry
CDCL132649 Mouse MID1 ORF clone (NM_001193280.1) Inquiry
CDCL132651 Mouse MID1 ORF clone (NM_033289.1) Inquiry
CDCL132653 Human MID1 ORF clone (NM_001193278.1) Inquiry
CDCR379198 Rat Mid1 ORF Clone(NM_022927.1) Inquiry
CDCS405625 Human MID1 ORF Clone (BC053626) Inquiry
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