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MICU1

Official Full Name
mitochondrial calcium uptake 1
Organism
Homo sapiens
GeneID
10367
Background
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
Synonyms
CALC; EFHA3; MPXPS; CBARA1; ara CALC;

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