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MGEA5

Official Full Name
O-GlcNAcase
Organism
Homo sapiens
GeneID
10724
Background
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]
Synonyms
OGA; MEA5; MGEA5; NCOAT;

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