Pages
Products

MASP1


Official Full Name
MBL associated serine protease 1
Organism
Homo sapiens
Gene ID
5648
Background
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
Synonyms
3MC1; MAP1; MASP; RaRF; CRARF; MAP-1; MASP3; MAp44; PRSS5; CRARF1; MASP-3

Cat.No. Product Name Price
SHH338487 shRNA set against Rat MASP1 (NM_022257.1) Inquiry
SHH178067 shRNA set against Mouse Masp1(NM_008555.2) Inquiry
SHH178085 shRNA set against Rat Masp1(NM_022257.1) Inquiry
SHH338479 shRNA set against Human MASP1 (NM_001879.5) Inquiry
SHH338483 shRNA set against Mouse MASP1 (NM_008555.2) Inquiry
SHW006082 shRNA set against Chicken MASP1 (NM_213586) Inquiry
Cat.No. Product Name Price
CDFR011940 Rat Masp1 cDNA Clone(NM_022257.1) Inquiry
MiUTR1M-06963 MASP1 miRNA 3'UTR clone Inquiry
MiUTR1R-03700 MASP1 miRNA 3'UTR clone Inquiry
MiUTR3H-03438 MASP1 miRNA 3'UTR clone Inquiry
MiUTR3H-03439 MASP1 miRNA 3'UTR clone Inquiry
MiUTR3H-03440 MASP1 miRNA 3'UTR clone Inquiry
CDCB167557 Chicken MASP1 ORF Clone (NM_213586) Inquiry
CDCB181051 Rabbit MASP1 ORF clone (XM_008266638.1) Inquiry
CDCR245669 Mouse Masp1 ORF Clone(NM_008555.2) Inquiry
CDCR378943 Rat Masp1 ORF Clone(NM_022257.1) Inquiry
CDCS418982 Human MASP1 ORF Clone (BC106945) Inquiry
Quick Inquiry