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MYOM1


Official Full Name
myomesin 1
Organism
Homo sapiens
Gene ID
8736
Background
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms
SKELEMIN

Cat.No. Product Name Price
SHH213725 shRNA set against Human MYOM1(NM_019856.1) Inquiry
SHH213741 shRNA set against Human MYOM1(NM_003803.3) Inquiry
SHH213749 shRNA set against Mouse Myom1(NM_001083934.1) Inquiry
SHH213767 shRNA set against Human MYOM1(NM_019856.1) Inquiry
SHH213769 shRNA set against Human MYOM1(NM_003803.3) Inquiry
SHH213779 shRNA set against Mouse Myom1(NM_010867.2) Inquiry
SHH348416 shRNA set against Human Myom1 (NM_003803.3) Inquiry
SHH348420 shRNA set against Mouse Myom1 (NM_010867.2) Inquiry
SHW005461 shRNA set against Chicken MYOM1 (NM_204959) Inquiry
Cat.No. Product Name Price
CDFG002361 Human MYOM1 cDNA Clone(NM_019856.1) Inquiry
CDFL008087 Mouse Myom1 cDNA Clone(NM_010867.2) Inquiry
MiUTR1H-06605 MYOM1 miRNA 3'UTR clone Inquiry
MiUTR1H-06606 MYOM1 miRNA 3'UTR clone Inquiry
MiUTR1M-07471 MYOM1 miRNA 3'UTR clone Inquiry
MiUTR1M-07472 MYOM1 miRNA 3'UTR clone Inquiry
CDCB166936 Chicken MYOM1 ORF Clone (NM_204959) Inquiry
CDCB189526 Rabbit MYOM1 ORF clone (XM_002713606.2) Inquiry
CDCL136089 Human MYOM1 ORF clone (NM_019856.1) Inquiry
CDCL151434 Human Myom1 ORF clone (NM_010867.2) Inquiry
CDCR235343 Mouse Myom1 ORF Clone(NM_001083934.1) Inquiry
CDCS411472 Human MYOM1 ORF Clone (BC116183) Inquiry
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