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MYLK


Official Full Name
myosin light chain kinase
Organism
Homo sapiens
Gene ID
4638
Background
This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
Synonyms
KRP; AAT7; MLCK; MLCK1; MMIHS; MYLK1; MMIHS1; MYLK-L; smMLCK; MLCK108; MLCK210; MSTP083

Cat.No. Product Name Price
SHH212213 shRNA set against Mouse Mylk(NM_139300.3) Inquiry
SHH348004 shRNA set against Mouse Mylk (NM_139300.3) Inquiry
SHH212141 shRNA set against Human MYLK(NM_053027.3) Inquiry
SHH212159 shRNA set against Human MYLK(NM_053025.3) Inquiry
SHH212195 shRNA set against Human MYLK(NM_053031.2) Inquiry
SHH212231 shRNA set against Human MYLK(NM_053026.3) Inquiry
SHH212267 shRNA set against Human MYLK(NM_053028.3) Inquiry
SHH212285 shRNA set against Human MYLK(NM_053032.2) Inquiry
SHH348000 shRNA set against Human Mylk (NM_053025.3) Inquiry
SHH348008 shRNA set against Rat Mylk (NM_001105874.2) Inquiry
SHW005952 shRNA set against Chicken MYLK (NM_205459) Inquiry
Cat.No. Product Name Price
CDFG007152 Human MYLK cDNA Clone(NM_053032.2) Inquiry
MiUTR1H-06586 MYLK miRNA 3'UTR clone Inquiry
MiUTR1H-06585 MYLK miRNA 3'UTR clone Inquiry
MiUTR1H-06584 MYLK miRNA 3'UTR clone Inquiry
MiUTR1H-06583 MYLK miRNA 3'UTR clone Inquiry
MiUTR1H-06582 MYLK miRNA 3'UTR clone Inquiry
CDFR005604 Rat Mylk cDNA Clone(NM_001105874.2) Inquiry
CDFG007155 Human MYLK cDNA Clone(NM_053031.2) Inquiry
CDFG007153 Human MYLK cDNA Clone(NM_053032.2) Inquiry
MiUTR1H-06587 MYLK miRNA 3'UTR clone Inquiry
MiUTR1M-07450 MYLK miRNA 3'UTR clone Inquiry
CDCR314538 Human MYLK ORF Clone(NM_053025.3) Inquiry
CDCR266575 Mouse Mylk ORF Clone(NM_139300.3) Inquiry
CDCL135901 Human MYLK ORF clone (NM_053032.2) Inquiry
CDCL135899 Mouse MYLK ORF clone (NM_053026.3) Inquiry
CDCL135897 Human MYLK ORF clone (NM_053027.3) Inquiry
CDCL135895 Mouse MYLK ORF clone (NM_053028.3) Inquiry
CDCL135893 Mouse MYLK ORF clone (NM_053031.2) Inquiry
CDCB180261 Rabbit MYLK ORF clone (NM_001082306.1) Inquiry
CDCR372520 Rat Mylk ORF Clone(NM_001105874.2) Inquiry
CDCB167427 Chicken MYLK ORF Clone (NM_205459) Inquiry
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