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myh11a

Official Full Name
myosin, heavy chain 11a, smooth muscle
Organism
Danio rerio
GeneID
554168
Background
Predicted to enable actin filament binding activity and microfilament motor activity. Acts upstream of or within several processes, including digestive tract morphogenesis; heart contraction; and regulation of polarized epithelial cell differentiation. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Is expressed in gut and muscle. Used to study megacystis-microcolon-intestinal hypoperistalsis syndrome. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome; patent ductus arteriosus; and thoracic aortic aneurysm. Orthologous to human MYH11 (myosin heavy chain 11). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
myh11;

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