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MTHFS

Official Full Name
methenyltetrahydrofolate synthetase
Organism
Homo sapiens
GeneID
10588
Background
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Synonyms
NEDMEHM; HsT19268;

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