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MTA2


Official Full Name
metastasis associated 1 family member 2
Organism
Homo sapiens
Gene ID
9219
Background
This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]
Synonyms
PID; MTA1L1

Cat.No. Product Name Price
SHH346068 shRNA set against Mouse MTA2 (NM_011842.3) Inquiry
SHH346064 shRNA set against Human MTA2 (NM_004739.3) Inquiry
SHH346072 shRNA set against Rat MTA2 (NM_001100740.1) Inquiry
SHW018611 shRNA set against Danio rerio MTA2 (NM_214695) Inquiry
Cat.No. Product Name Price
CDCB187249 Rabbit MTA2 ORF clone (XM_002721010.2) Inquiry
CDFR005345 Rat Mta2 cDNA Clone(NM_001100740.1) Inquiry
MiUTR1M-07348 MTA2 miRNA 3'UTR clone Inquiry
MiUTR3H-06407 MTA2 miRNA 3'UTR clone Inquiry
CDCB180086 Danio rerio MTA2 ORF Clone (NM_214695) Inquiry
CDCH390716 Human MTA2 ORF clone(NM_004739.3) Inquiry
CDCL134801 Human Mta2 ORF clone (NM_011842.3) Inquiry
CDCR372365 Rat Mta2 ORF Clone(NM_001100740.1) Inquiry
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