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MRPL54

Official Full Name
mitochondrial ribosomal protein L54
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Synonyms
MRPL54; mitochondrial ribosomal protein L54; 39S ribosomal protein L54, mitochondrial; 39S ribosomal protein L54 mitochondrial precursor; L54mt; MRP L54; MRP-L54

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