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MLXIPL

Official Full Name
MLX interacting protein like
Organism
Homo sapiens
GeneID
51085
Background
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Synonyms
MIO; MLX; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14;

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