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MKRN1


Official Full Name
makorin ring finger protein 1
Organism
Homo sapiens
Gene ID
23608
Background
This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Synonyms
RNF61

Cat.No. Product Name Price
SHH342328 shRNA set against Human MKRN1 (NM_013446.3) Inquiry
SHH342332 shRNA set against Mouse MKRN1 (NM_018810.2) Inquiry
SHH342336 shRNA set against Rat MKRN1 (NM_001004233.1) Inquiry
SHW005250 shRNA set against Chicken MKRN1 (NM_204742) Inquiry
SHW015330 shRNA set against Danio rerio MKRN1 (NM_152978) Inquiry
Cat.No. Product Name Price
CDFH011528 Human MKRN1 cDNA Clone(NM_001145125.1) Inquiry
CDFL007658 Mouse Mkrn1 cDNA Clone(NM_018810.2) Inquiry
CDFR001380 Rat Mkrn1 cDNA Clone(NM_001004233.1) Inquiry
MiUTR1M-07137 MKRN1 miRNA 3'UTR clone Inquiry
MiUTR1R-03901 MKRN1 miRNA 3'UTR clone Inquiry
MiUTR3H-09443 MKRN1 miRNA 3'UTR clone Inquiry
MiUTR3H-09444 MKRN1 miRNA 3'UTR clone Inquiry
CDCB166725 Chicken MKRN1 ORF Clone (NM_204742) Inquiry
CDCB176805 Danio rerio MKRN1 ORF Clone (NM_152978) Inquiry
CDCB187156 Rabbit MKRN1 ORF clone (XM_008250781.1) Inquiry
CDCL132893 Mouse MKRN1 ORF clone (NM_001145125.1) Inquiry
CDCL132895 Human MKRN1 ORF clone (NM_013446.3) Inquiry
CDCR253613 Mouse Mkrn1 ORF Clone(NM_018810.2) Inquiry
CDCR368431 Rat Mkrn1 ORF Clone(NM_001004233.1) Inquiry
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