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MIB1

Official Full Name
MIB E3 ubiquitin protein ligase 1
Organism
Homo sapiens
GeneID
57534
Background
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]
Synonyms
MIB; DIP1; ZZZ6; DIP-1; LVNC7; ZZANK2;

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