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MEP1B


Official Full Name
meprin A subunit beta
Organism
Homo sapiens
Gene ID
4225
Background
Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq, Oct 2011]
Synonyms
CSX3; NK2.3; NKX2C; NKX2.3; NKX4-3

Cat.No. Product Name Price
SHH184799 shRNA set against Mouse Mep1b(NM_008586.2) Inquiry
SHH184835 shRNA set against Human MEP1B(NM_005925.2) Inquiry
SHH340439 shRNA set against Human Mep1b (NM_005925.2) Inquiry
SHH340443 shRNA set against Mouse Mep1b (NM_008586.2) Inquiry
SHH340447 shRNA set against Rat Mep1b (NM_013183.2) Inquiry
SHW010398 shRNA set against Danio rerio MEP1B (NM_001076621) Inquiry
Cat.No. Product Name Price
CDFH011344 Human MEP1B cDNA Clone(NM_005925.2) Inquiry
MiUTR1H-06209 MEP1B miRNA 3'UTR clone Inquiry
MiUTR1M-07052 MEP1B miRNA 3'UTR clone Inquiry
CDCB171873 Danio rerio MEP1B ORF Clone (NM_001076621) Inquiry
CDCB187927 Rabbit MEP1B ORF clone (XM_008261183.1) Inquiry
CDCL185318 Human MEP1B ORF clone(NM_005925.2) Inquiry
CDCR245783 Mouse Mep1b ORF Clone(NM_008586.2) Inquiry
CDCR378016 Rat Mep1b ORF Clone(NM_013183.2) Inquiry
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