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MED23


Official Full Name
mediator complex subunit 23
Organism
Homo sapiens
Gene ID
9439
Background
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]
Synonyms
SUR2; CRSP3; MRT18; SUR-2; ARC130; CRSP130; CRSP133; DRIP130

Cat.No. Product Name Price
SHH340011 shRNA set against Human Med23 (NM_015979.3) Inquiry
SHH340015 shRNA set against Mouse Med23 (NM_027347.3) Inquiry
SHW007075 shRNA set against Danio rerio MED23 (NM_001003990) Inquiry
Cat.No. Product Name Price
CDCL151368 Mouse Med23 ORF clone (NM_027347.3) Inquiry
CDFG020455 Mouse Med23 cDNA Clone(NM_001166416.1) Inquiry
MiUTR3H-07312 MED23 miRNA 3'UTR clone Inquiry
MiUTR3H-07313 MED23 miRNA 3'UTR clone Inquiry
CDCB168550 Danio rerio MED23 ORF Clone (NM_001003990) Inquiry
CDCB191968 Rabbit MED23 ORF clone (XM_002714819.2) Inquiry
CDCL151366 Mouse Med23 ORF clone (NM_001166416.1) Inquiry
CDCR288945 Human MED23 ORF Clone(NM_004830.3) Inquiry
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