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MAPK9


Official Full Name
mitogen-activated protein kinase 9
Organism
Homo sapiens
Gene ID
5601
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
Synonyms
JNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA

Cat.No. Product Name Price
SHH338123 shRNA set against Human MAPK9 (NM_002752.4) Inquiry
SHH338127 shRNA set against Mouse MAPK9 (NM_016961.3) Inquiry
SHH338131 shRNA set against Rat MAPK9 (NM_017322.2) Inquiry
SHW005595 shRNA set against Chicken MAPK9 (NM_205095) Inquiry
Cat.No. Product Name Price
SKO0587 MAPK9 Validated sgRNA vector Inquiry
MiUTR1H-06097 MAPK9 miRNA 3'UTR clone Inquiry
MiUTR1H-06096 MAPK9 miRNA 3'UTR clone Inquiry
MiUTR1H-06095 MAPK9 miRNA 3'UTR clone Inquiry
MiUTR1H-06094 MAPK9 miRNA 3'UTR clone Inquiry
CDFH011051 Human MAPK9 cDNA Clone(NM_001135044.1) Inquiry
MiUTR3H-05389 MAPK9 miRNA 3'UTR clone Inquiry
CDCS408041 Human MAPK9 ORF Clone (BC032539) Inquiry
CDCR378423 Rat Mapk9 ORF Clone(NM_017322.2) Inquiry
CDCL185273 Mouse MAPK9 ORF clone(NM_016961.3) Inquiry
CDCL130557 Human MAPK9 ORF clone (NM_001135044.1) Inquiry
CDCL130553 Mouse MAPK9 ORF clone (NM_139070.2) Inquiry
CDCL130547 Human Mapk9 ORF clone (NM_001163671.1) Inquiry
CDCL130545 Human Mapk9 ORF clone (NM_001163672.1) Inquiry
CDCB192098 Rabbit MAPK9 ORF clone (XM_002721307.2) Inquiry
CDCR277616 Mouse Mapk9 ORF Clone(NM_207692.2) Inquiry
CDCB167070 Chicken MAPK9 ORF Clone (NM_205095) Inquiry
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