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mapk8b


Official Full Name
mitogen-activated protein kinase 8b
Organism
Danio rerio
Gene ID
65236
Background
Predicted to enable JUN kinase activity. Acts upstream of or within JNK cascade; determination of dorsal identity; and enteric nervous system development. Predicted to be located in synapse. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; gut; head; pectoral fin; and pericardial region. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm; chronic mucocutaneous candidiasis; colorectal adenoma; rectal benign neoplasm; and type 2 diabetes mellitus. Orthologous to human MAPK8 (mitogen-activated protein kinase 8). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
JNK; JNK1; jnk1b; mapk8; jnk1a-1; zgc:112379

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