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MAPK10


Official Full Name
mitogen-activated protein kinase 10
Organism
Homo sapiens
Gene ID
5602
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
Synonyms
JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK

Cat.No. Product Name Price
SHH175195 shRNA set against Mouse Mapk10(NM_009158.2) Inquiry
SHH175241 shRNA set against Mouse Mapk10(NM_001081567.1) Inquiry
SHH337931 shRNA set against Human MAPK10 (NM_002753.3) Inquiry
SHH337935 shRNA set against Mouse MAPK10 (NM_009158.2) Inquiry
SHH337939 shRNA set against Rat MAPK10 (NM_012806.2) Inquiry
SHW009479 shRNA set against Danio rerio MAPK10 (NM_001037701) Inquiry
Cat.No. Product Name Price
MiUTR1H-06079 MAPK10 miRNA 3'UTR clone Inquiry
MiUTR1H-06080 MAPK10 miRNA 3'UTR clone Inquiry
MiUTR1M-06933 MAPK10 miRNA 3'UTR clone Inquiry
MiUTR1M-06934 MAPK10 miRNA 3'UTR clone Inquiry
CDCB170954 Danio rerio MAPK10 ORF Clone (NM_001037701) Inquiry
CDCB194809 Rabbit MAPK10 ORF clone (XM_002717056.2) Inquiry
CDCH388644 Rat MAPK10 ORF clone(NM_012806.2) Inquiry
CDCL185262 Mouse MAPK10 ORF clone(NM_009158.2) Inquiry
CDCR235055 Mouse Mapk10 ORF Clone(NM_001081567.1) Inquiry
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