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MAP3K14

Official Full Name
mitogen-activated protein kinase kinase kinase 14
Organism
Homo sapiens
GeneID
9020
Background
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
Synonyms
HS; NIK; HSNIK; IMD112; FTDCR1B;

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