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MAP2K4


Official Full Name
mitogen-activated protein kinase kinase 4
Organism
Homo sapiens
Gene ID
6416
Background
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Synonyms
JNKK; MEK4; MKK4; SEK1; SKK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1

Cat.No. Product Name Price
AD09615Z Human MAP2K4 adenoviral particles Inquiry
Cat.No. Product Name Price
SHH173513 shRNA set against Rat Map2k4(NM_001030023.1) Inquiry
SHH173531 shRNA set against Mouse Map2k4(NM_009157.4) Inquiry
SHH173549 shRNA set against Human MAP2K4(NM_003010.2) Inquiry
SHH337563 shRNA set against Human MAP2K4 (NM_003010.2) Inquiry
SHH337567 shRNA set against Mouse MAP2K4 (NM_009157.4) Inquiry
SHH337571 shRNA set against Rat MAP2K4 (NM_001030023.1) Inquiry
Cat.No. Product Name Price
CDFH010964 Human MAP2K4 cDNA Clone(NM_003010.2) Inquiry
CDFH010965 Human MAP2K4 cDNA Clone(NM_003010.2) Inquiry
CDFH010966 Human MAP2K4 cDNA Clone(NM_003010.2) Inquiry
CDFH010967 Human MAP2K4 cDNA Clone(NM_003010.2) Inquiry
CDFH010968 Human MAP2K4 cDNA Clone(NM_003010.2) Inquiry
CDFH010969 Human MAP2K4 cDNA Clone(NM_003010.2) Inquiry
CDFL007340 Mouse Map2k4 cDNA Clone(NM_009157.4) Inquiry
CDFR004151 Rat Map2k4 cDNA Clone(NM_001030023.1) Inquiry
MiUTR1H-06055 MAP2K4 miRNA 3'UTR clone Inquiry
MiUTR1M-06910 MAP2K4 miRNA 3'UTR clone Inquiry
MiUTR1R-03669 MAP2K4 miRNA 3'UTR clone Inquiry
CDCB190847 Rabbit MAP2K4 ORF clone (XM_002718920.2) Inquiry
CDCL185252 Mouse MAP2K4 ORF clone(NM_009157.4) Inquiry
CDCR284632 Human MAP2K4 ORF Clone(NM_003010.2) Inquiry
CDCR371176 Rat Map2k4 ORF Clone(NM_001030023.1) Inquiry
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