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m17


Official Full Name
IL-6 subfamily cytokine M17
Organism
Danio rerio
Gene ID
555717
Background
Predicted to enable ciliary neurotrophic factor receptor binding activity; cytokine activity; and growth factor activity. Predicted to be involved in several processes, including astrocyte activation; cell surface receptor signaling pathway; and positive regulation of axon regeneration. Predicted to act upstream of or within cell differentiation and nervous system development. Predicted to be located in cytoplasm and membrane. Predicted to be active in axon; glial cell projection; and neuronal cell body. Is expressed in several structures, including brain; cranial ganglion; eye; pleuroperitoneal region; and presumptive neural retina. Human ortholog(s) of this gene implicated in Huntington's disease; disease of mental health; glaucoma; multiple sclerosis; and obesity. Orthologous to human CNTF (ciliary neurotrophic factor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
lif; si:dkeyp-15f12.5

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SHW010784 shRNA set against Danio rerio M17 (NM_001079833) Inquiry
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