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LRIG2

Official Full Name
leucine rich repeats and immunoglobulin like domains 2
Organism
Homo sapiens
GeneID
9860
Background
This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Synonyms
LIG2; UFS2; LIG-2;

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