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LPHN1


Official Full Name
adhesion G protein-coupled receptor L1
Organism
Homo sapiens
Gene ID
22859
Background
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
Synonyms
ADGRL1; CL1; LEC2; CIRL1; LPHN1; DEDBANP

Cat.No. Product Name Price
SHH159689 shRNA set against Rat Lphn1(NM_022962.1) Inquiry
SHH159707 shRNA set against Mouse Lphn1(NM_181039.2) Inquiry
SHH333537 shRNA set against Human LPHN1 (NM_014921.4) Inquiry
SHH333539 shRNA set against Mouse LPHN1 (NM_181039.2) Inquiry
SHH333543 shRNA set against Rat LPHN1 (NM_022962.1) Inquiry
Cat.No. Product Name Price
CDFR012185 Rat Lphn1 cDNA Clone(NM_022962.1) Inquiry
MiUTR1R-03549 LPHN1 miRNA 3'UTR clone Inquiry
MiUTR4H-TG05118 LPHN1 miRNA 3'UTR clone Inquiry
CDCB159960 Human LPHN1 ORF clone (BC019928) Inquiry
CDCB182388 Rabbit LPHN1 ORF clone (XM_002724222.2) Inquiry
CDCL128175 Mouse LPHN1 ORF clone (NM_001008701.2) Inquiry
CDCL128179 Human Lphn1 ORF clone (NM_181039.2) Inquiry
CDCR379232 Rat Lphn1 ORF Clone(NM_022962.1) Inquiry
CDCS406381 Human LPHN1 ORF Clone (BC019928) Inquiry
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