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LRWD1


Official Full Name
leucine rich repeats and WD repeat domain containing 1
Organism
Homo sapiens
Gene ID
222229
Background
The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Synonyms
ORCA; CENP-33

Cat.No. Product Name Price
SHH335163 shRNA set against Human LRWD1 (NM_152892.1) Inquiry
SHH335167 shRNA set against Mouse LRWD1 (NM_027891.4) Inquiry
Cat.No. Product Name Price
CDCB158628 Human LRWD1 ORF clone (BC030547) Inquiry
CDFG009737 Human LRWD1 cDNA Clone(NM_152892.1) Inquiry
MiUTR1H-02845 LRWD1 miRNA 3'UTR clone Inquiry
MiUTR1M-00103 LRWD1 miRNA 3'UTR clone Inquiry
CDCB194888 Rabbit LRWD1 ORF clone (XM_002723986.2) Inquiry
CDCL185206 Mouse LRWD1 ORF clone(NM_027891.4) Inquiry
CDCR320276 Human LRWD1 ORF Clone(NM_152892.1) Inquiry
CDCS417272 Human LRWD1 ORF Clone (BC030547) Inquiry
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