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LMOD3


Official Full Name
leiomodin 3
Organism
Homo sapiens
Gene ID
56203
Background
The protein encoded by this gene is a member of the leiomodin family of proteins. This protein contains three actin-binding domains, a tropomyosin domain, a leucine-rich repeat domain, and a Wiskott-Aldrich syndrome protein homology 2 domain (WH2). Localization of this protein to the pointed ends of thin filaments has been observed, and there is evidence that this protein acts as a catalyst of actin nucleation, and is important to the organization of sarcomeric thin filaments in skeletal muscles. Mutations in this gene have been associated as one cause of Nemaline myopathy, as other genes have also been linked to this disorder. Nemaline myopathy is a disorder characterized by nonprogressive generalized muscle weakness and protein inclusions (nemaline bodies) in skeletal myofibers. Patients with mutations in this gene often present with a severe congenital form of the disorder. [provided by RefSeq, Jan 2015]
Synonyms
NEM10

Cat.No. Product Name Price
SHH152489 shRNA set against Mouse Lmod3(NM_001081157.1) Inquiry
SHH331115 shRNA set against Human LMOD3 (NM_198271.3) Inquiry
SHH331119 shRNA set against Mouse LMOD3 (NM_001081157.1) Inquiry
Cat.No. Product Name Price
MiUTR1M-06692 LMOD3 miRNA 3'UTR clone Inquiry
CDCB193392 Rabbit LMOD3 ORF clone (XM_008260919.1) Inquiry
CDCL127749 Mouse Lmod3 ORF clone (NM_001081157.1) Inquiry
CDCS417776 Human LMOD3 ORF Clone (BC121019) Inquiry
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