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LMNA


Official Full Name
lamin A/C
Organism
Homo sapiens
Gene ID
4000
Background
The protein encoded by this gene is part of the nuclear lamina, a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, May 2022]
Synonyms
FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; MADA; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B

Cat.No. Product Name Price
SHH151985 shRNA set against Human LMNA(NM_005572.3) Inquiry
SHH152003 shRNA set against Rat Lmna(NM_001002016.1) Inquiry
SHH331007 shRNA set against Mouse LMNA (NM_019390.2) Inquiry
SHH152021 shRNA set against Mouse Lmna(NM_001002011.2) Inquiry
SHH152075 shRNA set against Mouse Lmna(NM_019390.2) Inquiry
SHH331003 shRNA set against Human LMNA (NM_005572.3) Inquiry
SHH331011 shRNA set against Rat LMNA (NM_001002016.1) Inquiry
SHW005782 shRNA set against Chicken LOC396224 (NM_205287) Inquiry
SHW015323 shRNA set against Danio rerio LMNA (NM_152971) Inquiry
Cat.No. Product Name Price
SKO0107 LMNA Validated sgRNA vector Inquiry
CDCB167257 Chicken LOC396224 ORF Clone (NM_205287) Inquiry
MiUTR3H-01289 LMNA miRNA 3'UTR clone Inquiry
MiUTR1R-03037 LMNA miRNA 3'UTR clone Inquiry
MiUTR1M-06685 LMNA miRNA 3'UTR clone Inquiry
MiUTR1M-06684 LMNA miRNA 3'UTR clone Inquiry
MiUTR1H-05714 LMNA miRNA 3'UTR clone Inquiry
CDCR253734 Mouse Lmna ORF Clone(NM_019390.2) Inquiry
CDFR001186 Rat Lmna cDNA Clone(NM_001002016.1) Inquiry
MiUTR3H-01290 LMNA miRNA 3'UTR clone Inquiry
CDCS410155 Human LMNA ORF Clone (BC000511) Inquiry
CDCR368233 Rat Lmna ORF Clone(NM_001002016.1) Inquiry
CDCL219165 Mouse Lmna ORF Clone(NM_001002011.2) Inquiry
CDCL127671 Mouse Lmna ORF clone (NM_001111102.1) Inquiry
CDCB197251 Rabbit LOC103346414 ORF clone (XM_008252492.1) Inquiry
CDCB191579 Rabbit LMNA ORF clone (XM_008264325.1) Inquiry
CDCB176798 Danio rerio LMNA ORF Clone (NM_152971) Inquiry
CDCS410156 Human LMNA ORF Clone (BC014507) Inquiry
CDCB160278 Human LMNA ORF clone (NM_170707) Inquiry
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