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LEP


Official Full Name
leptin
Organism
Homo sapiens
Gene ID
3952
Background
This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations in this gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in this gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Aug 2017]
Synonyms
OB; OBS; LEPD

Cat.No. Product Name Price
LV00355Z Human LEP lentiviral particles Inquiry
Cat.No. Product Name Price
SHH329615 shRNA set against Rat LEP (NM_013076.3) Inquiry
SHH146333 shRNA set against Mouse Lep(NM_008493.3) Inquiry
SHH329607 shRNA set against Human LEP (NM_000230.2) Inquiry
SHH329611 shRNA set against Mouse LEP (NM_008493.3) Inquiry
SHW012836 shRNA set against Danio rerio LEPA (NM_001128576) Inquiry
Cat.No. Product Name Price
CDFR010878 Rat Lep cDNA Clone(NM_013076.3) Inquiry
MiUTR1M-06599 LEP miRNA 3'UTR clone Inquiry
CDCB174311 Danio rerio LEPA ORF Clone (NM_001128576) Inquiry
CDCB180260 Rabbit LEP ORF clone (XM_008258163.1) Inquiry
CDCL185127 Human Leptin ORF clone(NM_000230.2) Inquiry
CDCL185128 Mouse Leptin ORF clone(NM_008493.3) Inquiry
CDCR377955 Rat Lep ORF Clone(NM_013076.3) Inquiry
CDCS405514 Human LEP ORF Clone (BC069323) Inquiry
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