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LDOC1

Official Full Name
LDOC1 regulator of NFKB signaling
Organism
Homo sapiens
GeneID
23641
Background
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]
Synonyms
Mar7; RTL7; BCUR1; Mart7; SIRH7;

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