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ldlra


Official Full Name
low density lipoprotein receptor a
Organism
Danio rerio
Gene ID
387529
Background
Enables low-density lipoprotein particle receptor activity. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; cholesterol homeostasis; and receptor-mediated endocytosis involved in cholesterol transport. Predicted to be located in clathrin-coated pit. Predicted to be part of low-density lipoprotein particle. Predicted to be active in early endosome and plasma membrane. Is expressed in female organism; intestine; liver; and male organism. Human ortholog(s) of this gene implicated in Alzheimer's disease; arteriosclerosis; familial hypercholesterolemia; hepatitis C; and migraine without aura. Orthologous to human LDLR (low density lipoprotein receptor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
ldlr

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