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lbx1b


Official Full Name
ladybird homeobox 1b
Organism
Danio rerio
Gene ID
793810
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in muscle cell differentiation. Acts upstream of or within convergent extension and regulation of Wnt signaling pathway. Predicted to be active in nucleus. Is expressed in nervous system; neural plate; neural tube; pectoral fin; and spinal cord neural keel. Human ortholog(s) of this gene implicated in congenital central hypoventilation syndrome. Orthologous to human LBX1 (ladybird homeobox 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
lbx1a; im:7139117

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