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KLF1

Official Full Name
KLF transcription factor 1
Organism
Homo sapiens
GeneID
10661
Background
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]
Synonyms
EKLF; CDAN4A; CDAN4B; EKLF/KLF1;

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