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KRT6A


Official Full Name
keratin 6A
Organism
Homo sapiens
Gene ID
3853
Background
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Oct 2014]
Synonyms
K6A; K6C; K6D; PC3; CK6A; CK6C; CK6D; CK-6C; CK-6E; KRT6C; KRT6D

Cat.No. Product Name Price
SHH327595 shRNA set against Human KRT6A (NM_005554.3) Inquiry
SHH327599 shRNA set against Mouse KRT6A (NM_008476.3) Inquiry
SHH332743 shRNA set against Rat LOC683313 (NM_001101007.1) Inquiry
SHH394160 shRNA set against Rat RGD1563072 (NM_001107981.1) Inquiry
SHH394236 shRNA set against Rat RGD1563482 (NM_001109065.2) Inquiry
SHL198918 shRNA set against Human KRT6A(NM_005554.3) Inquiry
SHL198936 shRNA set against Mouse Krt6a(NM_008476.3) Inquiry
SHW000035 shRNA set against Chicken KRT6A (NM_001001313) Inquiry
Cat.No. Product Name Price
CDFH010100 Human KRT6A cDNA Clone(NM_005554.3) Inquiry
CDFR005435 Rat LOC683313 cDNA Clone(NM_001101007.1) Inquiry
CDFR007586 Rat RGD1563072 cDNA Clone(NM_001107981.1) Inquiry
CDFR008612 Rat RGD1563482 cDNA Clone(NM_001109065.2) Inquiry
MiUTR1H-05460 KRT6A miRNA 3'UTR clone Inquiry
MiUTR1M-06453 KRT6A miRNA 3'UTR clone Inquiry
CDCB160212 Human KRT6A ORF clone (BC014152) Inquiry
CDCB161510 Chicken KRT6A ORF Clone (NM_001001313) Inquiry
CDCB196960 Rabbit LOC103347214 ORF clone (XM_008253695.1) Inquiry
CDCL125551 Human Krt6a ORF clone (NM_008476.3) Inquiry
CDCL185084 Human KRT6A ORF clone(NM_005554.3) Inquiry
CDCR372455 Rat LOC683313 ORF Clone(NM_001101007.1) Inquiry
CDCR374675 Rat RGD1563072 ORF Clone(NM_001107981.1) Inquiry
CDCR375569 Rat RGD1563482 ORF Clone(NM_001109065.2) Inquiry
CDCS412323 Human KRT6A ORF Clone (BC014152) Inquiry
CDCS412324 Human KRT6A ORF Clone (BC008807) Inquiry
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