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KREMEN2


Official Full Name
kringle containing transmembrane protein 2
Organism
Homo sapiens
Gene ID
79412
Background
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Synonyms
KRM2

Cat.No. Product Name Price
SHH327155 shRNA set against Human KREMEN2 (NM_024507.3) Inquiry
SHH327159 shRNA set against Mouse KREMEN2 (NM_028416.2) Inquiry
SHH327163 shRNA set against Rat KREMEN2 (NM_001105767.1) Inquiry
Cat.No. Product Name Price
CDCL125359 Human KREMEN2 ORF clone (NM_001253726.1) Inquiry
CDFR005500 Rat Kremen2 cDNA Clone(NM_001105767.1) Inquiry
CDCB192662 Rabbit KREMEN2 ORF clone (XM_008250659.1) Inquiry
CDCL125357 Human KREMEN2 ORF clone (NM_001253725.1) Inquiry
CDCR261447 Mouse Kremen2 ORF Clone(NM_028416.2) Inquiry
CDCR372587 Rat Kremen2 ORF Clone(NM_001105767.1) Inquiry
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