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KNSTRN


Official Full Name
kinetochore localized astrin (SPAG5) binding protein
Organism
Homo sapiens
Gene ID
90417
Background
Enables microtubule plus-end binding activity and protein homodimerization activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; mitotic sister chromatid segregation; and regulation of attachment of spindle microtubules to kinetochore. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and ruffle. Implicated in actinic keratosis and skin squamous cell carcinoma. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
SKAP; HSD11; ROCHIS; C15orf23; TRAF4AF1

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