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KLHL12


Official Full Name
kelch like family member 12
Organism
Homo sapiens
Gene ID
59349
Background
This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Synonyms
DKIR; C3IP1

Cat.No. Product Name Price
SHH326063 shRNA set against Human KLHL12 (NM_021633.2) Inquiry
SHH326067 shRNA set against Mouse KLHL12 (NM_153128.2) Inquiry
SHH326071 shRNA set against Rat KLHL12 (NM_153730.2) Inquiry
SHL200654 shRNA set against Human KLHL12(NM_021633.2) Inquiry
SHL200770 shRNA set against Mouse Klhl12(NM_153128.2) Inquiry
SHW007604 shRNA set against Danio rerio KLHL12 (NM_001007328) Inquiry
Cat.No. Product Name Price
CDCL124753 Mouse Klhl12 ORF clone (NM_153128.2) Inquiry
CDFG001602 Human KLHL12 cDNA Clone(NM_021633.2) Inquiry
MiUTR1H-05369 KLHL12 miRNA 3'UTR clone Inquiry
MiUTR1M-06355 KLHL12 miRNA 3'UTR clone Inquiry
CDCB169079 Danio rerio KLHL12 ORF Clone (NM_001007328) Inquiry
CDCB184747 Rabbit KLHL12 ORF clone (XM_008268568.1) Inquiry
CDCR306987 Human KLHL12 ORF Clone(NM_021633.2) Inquiry
CDCR381714 Rat Klhl12 ORF Clone(NM_153730.2) Inquiry
CDCS415347 Human KLHL12 ORF Clone (BC003183) Inquiry
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