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KISS1


Official Full Name
KiSS-1 metastasis suppressor
Organism
Homo sapiens
Gene ID
3814
Background
This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH neurons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Jun 2022]
Synonyms
HH13; KiSS-1

Cat.No. Product Name Price
AD08699Z Human KISS1 adenoviral particles Inquiry
Cat.No. Product Name Price
SHH325579 shRNA set against Human KISS1 (NM_002256.3) Inquiry
SHH325583 shRNA set against Mouse KISS1 (NM_178260.3) Inquiry
SHH325587 shRNA set against Rat KISS1 (NM_181692.1) Inquiry
SHL198516 shRNA set against Mouse Kiss1(NM_178260.3) Inquiry
SHL198534 shRNA set against Rat Kiss1(NM_181692.1) Inquiry
SHL198606 shRNA set against Human KISS1(NM_002256.3) Inquiry
SHW012183 shRNA set against Danio rerio KISS1 (NM_001113489) Inquiry
Cat.No. Product Name Price
CDFL006574 Mouse Kiss1 cDNA Clone(NM_178260.3) Inquiry
CDFR014999 Rat Kiss1 cDNA Clone(NM_181692.1) Inquiry
MiUTR1H-05341 KISS1 miRNA 3'UTR clone Inquiry
MiUTR1M-06330 KISS1 miRNA 3'UTR clone Inquiry
MiUTR1R-02879 KISS1 miRNA 3'UTR clone Inquiry
CDCB173658 Danio rerio KISS1 ORF Clone (NM_001113489) Inquiry
CDCB181435 Rabbit KISS1 ORF clone (XM_008268539.1) Inquiry
CDCL124475 Mouse Kiss1 ORF clone (NM_178260.3) Inquiry
CDCR005785 Human KISS1 ORF clone(NM_002256.3) Inquiry
CDCR382046 Rat Kiss1 ORF Clone(NM_181692.1) Inquiry
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